Research Progress on Pathogenesis and Drug Therapy of Atopic Dermatitis in Children
Keywords:
Children atopic dermatitis, Pathogenesis, Medication, Research progressAbstract
Children with atopic dermatitis (AD) are a chronic inflammatory skin disease with obvious itching symptoms and high recurrence rate in clinical practice. Under the clinical research of atopic dermatitis in children, the clinical treatment plan has increased significantly. This article reviews the research progress of drug treatment of atopic dermatitis in children.
References
Schlessinger J, Shepard JS, Gower R, et al., 2020, Safety, Effectiveness, and Pharmacokinetics of Crisaborole in Infants Aged 3 to Months With Mild-to-Moderate Atopic Dermatitis: A Phase Open-Label Study (CrisADeCARE 1). American Journal of Clinical Dermatology, 21(2): 275–284.
Teixeira C, Yilmaz O, Bernardo D, et al., 2024, IL-13 Inhibition in the Treatment of Atopic Dermatitis – New and Emerging Biologic Agents. Journal of International Medical Research, 52(11): 919–934.
Rusiol L, Puig L, 2024, A Narrative Review of the IL-18 and IL-37 Implications in the Pathogenesis of Atopic Dermatitis and Psoriasis: Prospective Treatment Targets. International Journal of Molecular Sciences, 25(15): 8437.
Armario-Hita JC, Galan-Gutierrez M, Dodero-Anillo JM, et al., 2023, Updated Review on Treatment of Atopic Dermatitis. Journal of Investigational Allergology & Clinical Immunology, 33(3): 158–167.
Amy SP, Elaine CS, Diamant T, et al., 2020, Efficacy and Safety of Dupilumab With Concomitant Topical Corticosteroids in Children 6 to 11 Years Old With Severe Atopic Dermatitis: A Randomized, Double-Blinded, Placebo-Controlled Phase 3 Trial. Journal of American Academy Dermatology, 83(5): 1282–1293.
Kumar S, Gonzalez A, Farbo D, et al., 2024, The Effects of Proton and Photon Radiation Therapy on the Development of Pediatric Dermatitis. Radiation, 4(4): 336–345.
Divya S, Pavadee P, Deepak K, et al., 2021, Contact Dermatitis in Children. Pediatric Annals, 50(5): e198–e205.
Natalia MS, Svetlana VK, 2021, Experience in the Treatment of Dermatitis in Children: Clinical Examples. Meditsinskiy Sovet, 2021(1): 168–172.
Emel I, Sibel EE, Tuna HA, et al., 2021, Challenging Diagnosis and Rare Disease in Children: Dermatitis Artefacta. Journal of Paediatrics and Child Health, 57(10): 1710–1712.
Léa F, Anne-Claire B, Nadine P, et al., 2019, Senna Laxative-Induced Dermatitis in Children: A Dermatitis Mimicking Child Abuse. European Journal of Dermatology, 29(3): 327–329.
Slomski A, 2016, Melatonin to Improve Skin and Sleep in Pediatric Dermatitis. JAMA, 315(8): 742.
Reddel S, Chierico DF, Quagliariello A, et al., 2019, Gut Microbiota Profile in Children Affected by Atopic Dermatitis and Evaluation of Intestinal Persistence of a Probiotic Mixture. Scientific Reports, 9(1): 1–10.
Kumar S, Gonzalez A, Farbo D, et al., 2024, The Effects of Proton and Photon Radiation Therapy on the Development of Pediatric Dermatitis. Radiation, 4(4): 336–345.
Zabet D, Reinsberger H, 2017, Dermatitis Artefacta in Children From a Forensic Perspective: A Case Report. La Revue de Médecine Légale, 8(3): 127–131.
Baffa EM, Bianchi L, Venturini E, et al., 2025, A Pediatric Case of Severe Atopic Dermatitis on Dupilumab Treatment and Pulmonary Tuberculosis. Pediatric Dermatology, 1–2.
