Correction mechanism of tumor suppressor gene p53 on abnormal cell G1/S phase transition
Keywords:
p53 gene, Cell cycle, G1/S phase transition, Correction mechanismAbstract
This article aims to delve into the correction mechanism of the tumor suppressor gene p53 on abnormal cell G1/S phase transition. As an important tumor suppressor gene, p53 plays a crucial role in maintaining normal cell growth and preventing carcinogenesis. Through a comprehensive analysis of relevant research, this paper elucidates the monitoring and regulatory role of p53 in the cell G1/S phase transition process, as well as the specific mechanisms by which it corrects abnormalities in the G1/S phase transition through various downstream effector molecules and signaling pathways. This provides a theoretical foundation for a deeper understanding of cell cycle regulation and the molecular mechanisms underlying tumor development.
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