Frequency of Candida Strains Isolated from Candidiasis Patients at A Tertiary Hospital over the Last 10 Years
Keywords:
Blood culture, Candidemia, Candida bloodstream infections, Candida species, Non-albicans Candida speciesAbstract
Candidemia is a major cause of nosocomial infections resulting in increased morbidity and mortality. It remains a serious risk in inpatients and increases medical treatment costs. From 2009 to 2018, Candida strains (3,533) isolated from blood culture tests at the S Hospital were analyzed according to the period, year, sex, age, ward, etc. During the entire period, 54,739 of 717,996 blood culture tests showed a positive rate (7.6%) and the Candida isolation rate was 3,533 (6.4%) out of the positive blood culture tests. Among the Candida isolates, C. albicans was the most common (33.8%), followed by C. tropicalis (28.6%), C. glabrata (19.8%), C. parapsilosis (7.8%), and C. krusei (4.0%). In early (2009–2013) or late (2014–2018) isolation, C. tropicalis decreased by 3.8% and C. glabrata increased by 3.4%. The isolation frequency became higher in patients aged above 50, C. parapsilosis (31.3%) in age 1–10, C. tropicalis (30.3%) and C. glabrata (27.6%) in age 41–50, and C. tropicalis (28.6%) in age > 80 are relatively frequent. Most species had been isolated from males, except for C. krusei, which was isolated in a relatively high proportion from females (60.9%). Therefore, a systematic and continuous nosocomial infection control system should be established for appropriate treatment as per antifungal treatment guidelines. The system should continuously monitor the distribution of Candida species and provide rapid identification results.
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