Distribution and Risk Factors Analysis of Multidrug-resistant Bacterial Infections in ICU Ward Patients
Keywords:
ICU, Multiple drug resistance, Hospital infection, Risk factorAbstract
Objective: To analyze the distribution of multidrug-resistant bacteria and their related risk factors in patients in the intensive care unit (ICU) of hospitals. Method: A retrospective analysis was conducted on the clinical data of 902 inpatients admitted to the Intensive Care Unit (ICU) of Longquanyi District Traditional Chinese Medicine Hospital from October 2022 to October 2023. The ICU hospital obtained the distribution location of infectious pathogens and the characteristics of antibiotic resistance of infection-resistant bacteria. Results: Among the 902 hospitalized patients, 112 cases developed hospital-acquired infections, with an infection rate of 12.41%. A total of 168 strains of pathogenic bacteria were isolated from 112 hospital samples of infected patients. Among them, 28 cases were multidrug-resistant hospital infections, accounting for 16.67% of the total number of pathogenic bacteria. The types are carbapenem-resistant Acinetobacter baumannii, carbapenem-resistant Klebsiella pneumoniae, and carbapenem-resistant Pseudomonas aeruginosa, accounting for 46.42%, 28.57%, and 17.87%, respectively. Univariate analysis showed that long-term bed rest [1], nutritional risk, multiple hospitalizations within one year, systemic glucocorticoid use, duration of mechanical ventilation and ventilator use, duration of antibiotic use, the combination of antibiotics, duration of indwelling urinary catheters and indwelling catheters [2], duration of indwelling gastric catheters and indwelling catheters, duration of deep vein catheters and indwelling catheters, and length of ICU hospitalization were all influencing factors for the occurrence of hospital-acquired infections in the ICU. Multivariate analysis showed that mechanical ventilation, diabetes, length of ventilator use, length of ICU hospitalization and malignant tumors constituted independent risk factors for multidrug-resistant bacterial infection [3]. Conclusion: The infection rate of multidrug-resistant bacteria in ICU patients is high, and relevant prevention and control measures can be formulated based on their risk factors.
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